Abstract
A computer-aided docking study was carried out to quickly clarify the binding structure of the ligand-receptor complex between bisphenol A (BPA), a well-known endocrine disruptor, and estrogen-related receptor γ (ERRγ). The resulting complex indicated that BPA binds to the ligand-binding pocket of ERRγ without any disruptions of the activation conformation.
Keywords: Estrogen-related receptor γ, bisphenol A, endocrine disruptors, docking calculation
Protein & Peptide Letters
Title: A Docking Modelling Rationally Predicts Strong Binding of Bisphenol A to Estrogen-Related Receptor γ
Volume: 15 Issue: 3
Author(s): Takeru Nose and Yasuyuki Shimohigashi
Affiliation:
Keywords: Estrogen-related receptor γ, bisphenol A, endocrine disruptors, docking calculation
Abstract: A computer-aided docking study was carried out to quickly clarify the binding structure of the ligand-receptor complex between bisphenol A (BPA), a well-known endocrine disruptor, and estrogen-related receptor γ (ERRγ). The resulting complex indicated that BPA binds to the ligand-binding pocket of ERRγ without any disruptions of the activation conformation.
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Cite this article as:
Nose Takeru and Shimohigashi Yasuyuki, A Docking Modelling Rationally Predicts Strong Binding of Bisphenol A to Estrogen-Related Receptor γ, Protein & Peptide Letters 2008; 15 (3) . https://dx.doi.org/10.2174/092986608783744261
DOI https://dx.doi.org/10.2174/092986608783744261 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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