Title: Synthetic Approaches to the 2006 New Drugs
VOLUME: 7 ISSUE: 12
Author(s):Kevin K.-C. Liu, Subas M. Sakya and Jin Li
Affiliation:Pfizer Inc, La Jolla, CA 92037,USA.
Keywords:Synthesis, new drug, new chemical entities, medicine, therapeutic agents
Abstract: New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing future new drugs. To these ends, this review covers the syntheses of 16 NCEs marketed in 2006.
