Title: Inhibition of Aromatase (AR) by Benzyl Azole-Based Compounds
VOLUME: 4 ISSUE: 8
Author(s):Shaheen Adat, Caroline P. Owen and Sabbir Ahmed
Affiliation:Department of Pharmacy,School of Pharmacy and Chemistry, Kingston University, Penrhyn Road,Kingston upon Thames, Surrey, KT1 2EE, UK.
Keywords:Enzyme, Inhibition, Azole, Estrogen synthetase, Aromatase
Abstract: We report the results of the evaluation of a series of benzyl imidazole-based compounds against the enzyme aromatase (AR). The results show that the synthesised compounds were potent inhibitors of AR in comparison to the standard compound aminoglutethimide (AG).
