Abstract
The past years have seen only the beginning of our understanding of metabolic processes and the importance of these processes to the development of safe and effective medicines. The trend to bring more detailed information into earlier stages of drug discovery will continue to drive improvements in technology and in experimental and analytical procedures for the study of biotransformation of drugs. The challenges are significant, but so is the promise of the contributions that can be made by biotransformation studies.
Keywords: Biotransformation, LC-MS, LC-TOF, Metabolism, excretion (ADME, Mass Spectrometry, Accelerator Mass Spectrometry
Current Topics in Medicinal Chemistry
Title: The Emergence and Application of Technological Advances in Biotrans-formation StudiesThe Emergence and Application of Technological Advances in Biotrans-formation Studies
Volume: 2 Issue: 1
Author(s): Carmen L. Fernandez-Metzler and Richard C. King
Affiliation:
Keywords: Biotransformation, LC-MS, LC-TOF, Metabolism, excretion (ADME, Mass Spectrometry, Accelerator Mass Spectrometry
Abstract: The past years have seen only the beginning of our understanding of metabolic processes and the importance of these processes to the development of safe and effective medicines. The trend to bring more detailed information into earlier stages of drug discovery will continue to drive improvements in technology and in experimental and analytical procedures for the study of biotransformation of drugs. The challenges are significant, but so is the promise of the contributions that can be made by biotransformation studies.
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Fernandez-Metzler L. Carmen and King C. Richard, The Emergence and Application of Technological Advances in Biotrans-formation StudiesThe Emergence and Application of Technological Advances in Biotrans-formation Studies, Current Topics in Medicinal Chemistry 2002; 2 (1) . https://dx.doi.org/10.2174/1568026023394650
DOI https://dx.doi.org/10.2174/1568026023394650 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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