Natural Products as Trypanocidal, Antileishmanial and Antimalarial Drugs

Author(s): Alain Fournet, Victoria Munoz

Journal Name: Current Topics in Medicinal Chemistry

Volume 2 , Issue 11 , 2002

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Parasitic diseases caused by protozoa as Leishmania, Trypanosome or Plasmodium are responsible for more than three millions deaths annually throughout the developing countries. This review covers recent studies on plant-secondary metabolites isolated from medicinal plants and that have demonstrated moderate to high activity in in vitro and in vivo bioassays against these protozoa. The biological activity of the last promising antiparasitic leads are described.

Keywords: antileishmanial and antimalarial drugs, trypanocidal drugs

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Article Details

Year: 2002
Page: [1215 - 1237]
Pages: 23
DOI: 10.2174/1568026023393011
Price: $65

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PDF: 24