Chemotherapy of Chagas Disease: Status and New Developments

Author(s): Hugo Cerecetto, Mercedes Gonzalez

Journal Name: Current Topics in Medicinal Chemistry

Volume 2 , Issue 11 , 2002

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Chagas disease is a major parasitic problem in developing countries in Central and South America. Chemotherapy for such disease is still insufficient and not effective in its chronic part. Many efforts have been made in recent years to know more about possible new biochemical targets to design new selective drugs. This paper reviews old therapeutic approaches -Nifurtimox, Benznidazole and related compounds- and the latest rationally developed drugs that prove to be active against different parasitic forms

Keywords: chemotherapy of chagas disease

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Article Details

Year: 2002
Page: [1187 - 1213]
Pages: 27
DOI: 10.2174/1568026023393066
Price: $65

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