Design of Synthetic Peptides for Diagnostics

Author(s): R. H. Meloen, W. C. Puijk, J. P.M. Langeveld, J. P.M. Langedijk, P. Timmerman

Journal Name: Current Protein & Peptide Science

Volume 4 , Issue 4 , 2003

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Due to the advantageous properties of synthetic molecules compared to biological ones biological molecules in diagnostic tests are replaced increasingly by synthetic ones, usually synthetic peptides or related molecules. The replacement of biological antigens by synthetic peptides is most advanced at present, as well as the use of site-specific antibodies induced with synthetic peptides. Moreover recent results indicate that synthetic molecules may also replace antibodies. Ultimately this will lead to diagnostic assays built of synthetic molecules only.

Keywords: synthetic peptides, diagnostics, diagnostic tests, biological antigens, site-specific antibodies, diagnostic assays

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Article Details

Year: 2003
Page: [253 - 260]
Pages: 8
DOI: 10.2174/1389203033487144
Price: $65

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