Monoamine Oxidases: to Inhibit or Not to Inhibit

Author(s): R. R. Ramsay, M. B. Gravestock

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 3 , Issue 2 , 2003

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Monoamine oxidase (MAO) inhibitors were developed as antidepressants but many drugs, including the novel oxazolidinone antibacterial agents, share similar molecular properties and have MAO inhibitory activity. Factors important for binding antidepressants and modifications to decrease binding of oxazolidinones to avoid undesirable vascular effects are discussed.

Keywords: monoamine oxidase, mao, mao inhibitor, monoamine oxidase inhibitor, antidepressants, oxazolidinones

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Article Details

Year: 2003
Page: [129 - 136]
Pages: 8
DOI: 10.2174/1389557033405287
Price: $65

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PDF: 11