Urocortin: Cardiovascular Actions and Therapeutic Implications

Author(s): M. T. Rademaker

Journal Name: Letters in Drug Design & Discovery

Volume 1 , Issue 2 , 2004

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Urocortin, expressed throughout the heart and vasculature, has potent effects on the cardiovascular system including vasodilation, increases in cardiac contractility and coronary blood flow, and protection of the myocardium against ischemia / reperfusion damage. This range of actions suggests urocortin has therapeutic potential in states of cardiac dysfunction and injury.

Keywords: urocortin, heart, vasculature, vasodilation, inotropism, cardioprotection

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Article Details

Year: 2004
Page: [168 - 172]
Pages: 5
DOI: 10.2174/1570180043485482
Price: $65

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