Cytotoxicity and Toxicity to Animals and Humans of Ribosome-Inactivating Proteins

Title: Cytotoxicity and Toxicity to Animals and Humans of Ribosome-Inactivating Proteins

VOLUME: 4 ISSUE: 5

Author(s):Maria Giulia Battelli

Affiliation:Dipartimento di Patologia Sperimentale, Via San Giacomo 14, I-40126 Bologna, Italy.

Keywords:cytotoxicity, toxicity to animals, toxicity to humans, type 1 ribosome-inactivating proteins, toxic type 2 ribosome-inactivating proteins, non-toxic type 2 ribosome-inactivating proteins

Abstract: The toxicity to cells and animals of type 1 and toxic and non-toxic type 2 Ribosome-Inactivating Proteins (RIP) is discussed in correlation with their catalytic activity, resulting in ribosome inactivation and apoptosis. The symptoms and histopathological lesions induced by RIP to animals and humans is also reviewed.

Cite this article as:

Maria Giulia Battelli, “ Cytotoxicity and Toxicity to Animals and Humans of Ribosome-Inactivating Proteins”, Mini-Reviews in Medicinal Chemistry (2004) 4: 513. https://doi.org/10.2174/1389557043403819

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