Correlation Between Hydrophobicity Sequence and Accessibility Sequence of Membrane Proteins

Author(s): Qiang Xu.

Journal Name: Protein & Peptide Letters

Volume 11 , Issue 6 , 2004

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Abstract:

In this paper, we used correlation analysis to quantify the correlations between the hydrophobicity sequence and accessibility sequence of 26 α-helix bundle membrane proteins and 119 transmembrane helices. Statistical significances of these correlations were also assessed. A slightly positive correlation was found in the α-helix bundle membrane proteins due to the contribution of extramembranous domains. No correlation was found in the transmembrane domains.

Keywords: hydrophobicity, accessibility, membrane protein, correlation analysis.

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Article Details

VOLUME: 11
ISSUE: 6
Year: 2004
Page: [533 - 537]
Pages: 5
DOI: 10.2174/0929866043406427
Price: $65

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