Content of the Hmg-17 Chromosomal Protein in Porcine Tissues

Author(s): Vassiliki A. Boumba, Konstantin Seferiadis, Theodore Vougiouklakis.

Journal Name: Protein & Peptide Letters

Volume 11 , Issue 6 , 2004

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Abstract:

HMG-17 proteins are nucleosomal proteins, implicated in control of chromatin structure and transcription, in a way that has not yet been fully understood. In this report, quantification of HMG-17 in porcine tissues was performed, by ELISA, using previously produced and characterized specific rabbit anti- HMG-17 antibodies. Our results showed high levels of HMG-17 compared to the DNA and H1 content of the tissues (on the contrary to previous reports), and more specifically that there were 1.7 molecules of HMG-17 per molecule of histone H1.

Keywords: hmg-17, histone h1, quantification, elisa, tissue distribution.

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Article Details

VOLUME: 11
ISSUE: 6
Year: 2004
Page: [515 - 519]
Pages: 5
DOI: 10.2174/0929866043406193
Price: $65

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