The favourable nuclear properties of copper-67 and rhenium-188 for therapeutic application are described, together with methods for the chemical synthesis of a number of derivatives. Survival from invasive bladder cancer has changed little over the past 20 years. The intravesicular administration of Cu-67 or Re-188 radiopharmaceuticals in the treatment of bladder cancer offers some promise for improvement in this situation.
Keywords: Rhenium-188, Copper-67, Bladder, Cancer, Radioimmunotherapy
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Published on: 01 March, 2012
Page: [61 - 68]