DNA, PNA, and Their Derivatives for Precise Genotyping of SNPs

Author(s): A. Kuzuya, J.- M. Zhou, M. Komiyama

Journal Name: Mini-Reviews in Organic Chemistry

Volume 1 , Issue 1 , 2004

Become EABM
Become Reviewer


Two new approaches for SNP genotyping are described. The one is based on tandem site-selective RNA scission and the genotype is determined by MALDI-TOF / MS analyses of clipped short RNA. The other is visual SNP genotyping with combinations of peptide nucleic acid (PNA) and single-stranded DNA specific nucleases.

Keywords: snp genotyping, rna, pna, selective scission, acridine, nuclease

promotion: free to download

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2004
Page: [125 - 131]
Pages: 7
DOI: 10.2174/1570193043488999

Article Metrics

PDF: 11