Combinatorial Carbohydrate Synthesis

Author(s): S. Nacak Baytas, R. J. Linhardt

Journal Name: Mini-Reviews in Organic Chemistry

Volume 1 , Issue 1 , 2004

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Combinatorial chemistry has contributed to the preparation of biologically important oligosaccharide and glycoconjugate libraries, with a view of improving our understanding of the complex interaction between the carbohydrates and their proteinbased receptors. The combinatorial carbohydrate synthesis strategies, developed in the past decade, provide access to small and medium size libraries. This mini review critically examines both the solution phase and solid phase strategies that have been reported to date.

Keywords: combinatorial chemistry, carbohydrates, solution phase synthesis, solid phase synthesis, glycoconjugates

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Article Details

Year: 2004
Page: [27 - 39]
Pages: 13
DOI: 10.2174/1570193043488917

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PDF: 17