Title: Exploring the Phosphoproteome with Mass Spectrometry
VOLUME: 4 ISSUE: 3
Author(s):Eric C. Peters, Ansgar Brock and Scott B. Ficarro
Affiliation:Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego,CA 92121, USA.
Keywords:Phosphoproteome, phosphorylation, spectrometry
Abstract: Protein phosphorylation is a reversible post-translational modification crucial in the control of numerous regulatory pathways. Understanding the highly interconnected nature of such networks requires new broader-scale analysis techniques. This report summarizes recent advances in the use of mass spectrometry to assess phosphorylation events in ever more complex systems.
