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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

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Exploring the Phosphoproteome with Mass Spectrometry

Author(s): Eric C. Peters, Ansgar Brock and Scott B. Ficarro

Volume 4, Issue 3, 2004

Page: [313 - 324] Pages: 12

DOI: 10.2174/1389557043487330

Price: $65

Abstract

Protein phosphorylation is a reversible post-translational modification crucial in the control of numerous regulatory pathways. Understanding the highly interconnected nature of such networks requires new broader-scale analysis techniques. This report summarizes recent advances in the use of mass spectrometry to assess phosphorylation events in ever more complex systems.

Keywords: Phosphoproteome, phosphorylation, spectrometry

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