Cellular and Physiological Effects of Short-Chain Fatty Acids

Author(s): Steven J. Miller

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 4 , Issue 8 , 2004

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Short chain fatty acids (SCFA) have multiple in vivo and in vitro effects including cell cycle arrest and induction of protein synthesis, differentiation, and apoptosis. Butyrate or derivatives have promise for treating inflammatory bowel disease and colon cancer. Genomic and proteomic analysis have generated new knowledge on function and applications for SCFA.

Keywords: short chain fatty acids, butyrate, inflammation, cancer, colon and fiber

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Article Details

Year: 2004
Page: [839 - 845]
Pages: 7
DOI: 10.2174/1389557043403288
Price: $65

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PDF: 8