Recent Advances in Antiviral Nucleoside and Nucleotide Therapeutics

Author(s): Claire Simons, Qinpei Wu, Thet T. Htar

Journal Name: Current Topics in Medicinal Chemistry

Volume 5 , Issue 13 , 2005

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Abstract:

Recent developments in nucleoside/nucleotide therapeutics and antiviral drug targets are described covering progress in the development of nucleoside/nucleotide mimetics for the treatment of influenza virus, human immunodeficiency virus type 1, hepatitis B and C virus, herpes virus infections; including herpes simplex virus, cytomegalovirus and varicella zoster virus infections, and the highly pathogenic poxviruses (variola, vaccinia and mokey pox) and filoviruses (Ebola and Marburg).

Keywords: nucleoside/nucleotide therapeutics, influenza virus, human immunodeficiency virus, hepatitis b and c virus, herpes virus, poxvirus, filovirus, sirna, antisense oligonucleotides

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Article Details

VOLUME: 5
ISSUE: 13
Year: 2005
Page: [1191 - 1203]
Pages: 13
DOI: 10.2174/156802605774463051
Price: $65

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