Cardiovascular Toxicity from the Perspective of Oxidative Stress, Electron Transfer, and Prevention by Antioxidants

Author(s): Peter Kovacic, Lisa A. Thurn

Journal Name: Current Vascular Pharmacology

Volume 3 , Issue 2 , 2005

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This review demonstrates that oxidative stress, reactive oxygen species, and electron transfer can serve as unifying mechanistic themes for large numbers of cardiovascular toxins, both endogenous and exogenous. Lipid peroxidation is a prevalent insult. Common among the various conditions are atherosclerosis and arrhythmia. The preventive effects of antioxidants are documented.

Keywords: cardiovascular toxins, oxidative stress, electron transfer, lipoperoxidation, antioxidants, reactive oxygen species, radicals

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Article Details

Year: 2005
Page: [107 - 117]
Pages: 11
DOI: 10.2174/1570161053586912
Price: $65

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