Severe Hemorrhagic Cystitis Associated with BK Polyoma Virus Infection Following Lung Transplantation

Author(s): Lingtak-Neander Chan, Malek G. Massad, Kamran Mahmood, Nina Clark, Sally Steinhiser, Jacques Kpodonu, Cimenga Tshibaka, Howard A. Jaffe

Journal Name: Current Respiratory Medicine Reviews

Volume 1 , Issue 3 , 2005

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BK polyoma virus-associated hemorrhagic cystitis has been described in patients who have had renal, bone marrow and cardiac transplantation. We report the first case of hemorrhagic cystitis associated with the BK virus in a 51 year old woman with scleroderma, who received bilateral lung transplantation. The pathological findings of the bladder were large cells with enlarged nuclei and scant cytoplasm (Decoy cells). The diagnosis was confirmed by immunohistochemical stains of the urinary bladder tissue and by blood and urine PCR. The patient required a cystectomy.

Keywords: BK polyoma virus, hemorrhagic cystitis, lung transplantation

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Article Details

Year: 2005
Page: [261 - 264]
Pages: 4
DOI: 10.2174/157339805774598036
Price: $65

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