Abstract
A very short and efficient synthesis of preclamol is described. The key step is the palladiumcatalysed arylation of the zinc enolate of N-propyl-2-piperidinone.
Keywords: preclamol, arylations, lactams, palladium, zinc, coupling reaction
Letters in Organic Chemistry
Title: A Very Short and Efficient Synthesis of Preclamol
Volume: 2 Issue: 2
Author(s): Arnault de Filippis, Domingo Gomez Pardo and Janine Cossy
Affiliation:
Keywords: preclamol, arylations, lactams, palladium, zinc, coupling reaction
Abstract: A very short and efficient synthesis of preclamol is described. The key step is the palladiumcatalysed arylation of the zinc enolate of N-propyl-2-piperidinone.
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Cite this article as:
Filippis de Arnault, Pardo Gomez Domingo and Cossy Janine, A Very Short and Efficient Synthesis of Preclamol, Letters in Organic Chemistry 2005; 2 (2) . https://dx.doi.org/10.2174/1570178053202883
DOI https://dx.doi.org/10.2174/1570178053202883 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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