Gold-Catalyzed Coupling of Alkynes and Acyl Iminiums

Author(s): Chunmei Wei, Chao-Jun Li

Journal Name: Letters in Organic Chemistry

Volume 2 , Issue 5 , 2005

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Abstract:

A gold-catalyzed direct addition of alkynes to active acyl iminium ion, which was generated in situ with an acid chloride, to afford a propargylamides in excellent yields.

Keywords: propargyl amines, enantioselective synthesis, copper-catalyzed addition, solid-phase mannich condensation, copper-mediated coupling, diisopropylethylamine

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Article Details

VOLUME: 2
ISSUE: 5
Year: 2005
Page: [410 - 414]
Pages: 5
DOI: 10.2174/1570178054405959
Price: $65

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