Molecular Targets of FoxP3+ Regulatory T Cells

Author(s): Chang H. Kim

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 7 , Issue 11 , 2007

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The important roles of FoxP3+ T cells in many immunological or cancerous diseases are now well established. The research field is now moving in the direction to fine-control the generation, migration, expansion, and function of FoxP3+ cells in an effort to prevent and cure specific types of diseases. Potential molecular targets to regulate FoxP3+ T cells are reviewed in this article.

Keywords: FoxP3, regulatory T cells, tolerance, diseases, migration, chemokine receptors

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Article Details

Year: 2007
Page: [1136 - 1143]
Pages: 8
DOI: 10.2174/138955707782331731
Price: $65

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