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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Symptom and Structure Modifying Properties of Chondroitin Sulfate in Osteoarthritis

Author(s): Jean-Yves Reginster, Florence Heraud, Brigitte Zegels and Olivier Bruyere

Volume 7, Issue 10, 2007

Page: [1051 - 1061] Pages: 11

DOI: 10.2174/138955707782110088

Price: $65

Abstract

Chondroitin sulfate (CS) is a complex carbohydrate polymer with variable sulfation which impacts function. CS exhibits a wide range of biological activities. Many experimental and clinical data are available, affirming that CS represents an effective and safe symptomatic treatment of osteoarthritis (OA) with delayed and sustained effects.

Keywords: Chondroitin sulfate, sulfation patterns, cartilage, glycosaminoglycans, osteoarthritis, SYSADOAs


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