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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Cell-Based Biosensors in Clinical Chemistry

Author(s): Spiridon E. Kintzios

Volume 7, Issue 10, 2007

Page: [1019 - 1026] Pages: 8

DOI: 10.2174/138955707782110141

Price: $65

Abstract

Cell-based biosensors represent the next revolution in medical diagnostics, offering a number of significant advantages, such as high speed, portability and low cost. The present review focuses on the most successful technologies used for the detection of ultra-low concentrations of bioactive analytes (such as metabolic markers and pathogens) in clinical samples.

Keywords: Bioelectric recognition, cell-based sensors, cell transfection, hepatitis virus B (HBV), hepatitis virus C (HCV), high-throughput screening systems (HSTSS), membrane-engineering, superoxide anion


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