Title: Recent Progress in the Pharmacology of Imidazo[1,2-a]pyridines
VOLUME: 7 ISSUE: 9
Author(s):Cecile Enguehard-Gueiffier and Alain Gueiffier
Affiliation:Laboratory of Medicinal Chemistry,Faculty of Pharmacy, 31 Avenue Monge, 37200 Tours, France.
Keywords:Imidazo[1,2-a]pyridine, pharmacological properties, enzyme inhibitors, receptor ligands, anti-infectious agents
Abstract: Imidazo[1,2-a]pyridine is a bicyclic system with a bridgehead nitrogen atom, of growing interest in medicinal chemistry. The paper deals with the recent progress realised in the comprehension of the pharmacological properties of this scaffold. From the many imidazo[1,2-a]pyridine analogues described in the literature, those discussed herein will be presented in three parts concerning first the enzyme inhibitors, then the receptor ligands and finally the anti-infectious agents.
