An Expeditious “Green” Michael Addition of Nitro Methane to Benzimidazole Chalcones in the Presence of TBAB as Surface Catalyst

Author(s): P.K. Dubey, P.V.V. Prasada Reddy, K. Srinivas

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 6 , 2007

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A novel Michael addition of nitromethane to β-carbon of the benzimidazole chalcones 1 in the presence of K2CO3 and TBAB, under solvent-free conditions, by a simple physical mixing of compounds, leading to 1-(1-alkyl-1Hbenzimidazol- 2-yl)-4-nitro-3-aryl-butane-1-one 2 is described.

Keywords: Benzimidazole chalcones, nitromethane, K2CO3, TBAB, solvent-free, mortar and pestle

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Article Details

Year: 2007
Page: [445 - 447]
Pages: 3
DOI: 10.2174/157017807781467533
Price: $65

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