Regioselective Synthesis of Biologically Important Scaffold Spiro [Indole- Perimidines]: An Antitumor Agents

Title: Regioselective Synthesis of Biologically Important Scaffold Spiro [Indole- Perimidines]: An Antitumor Agents

Volume: 4 Issue: 5

Author(s): Kapil Arya and Anshu Dandia

Affiliation:

Keywords: Perimidine, indole 2,3-dione, microwave, 1,8-diaminonapthalene, montmorillonite KSF, cytotoxic

Abstract: Regioselective synthesis of spiro [indole -3(3H), 2 (3H)perimidine]2(1H)one (4a-e) for potential application in cancer treatment under conventionally and microwave irradiation using different solvents/solid support has been studied. A judicious choice of the reaction conditions allowed the titled product 4a-e to be generated in excellent yields.

Cite this article as:

Kapil Arya and Anshu Dandia , Regioselective Synthesis of Biologically Important Scaffold Spiro [Indole- Perimidines]: An Antitumor Agents, Letters in Organic Chemistry 2007; 4 (5) . https://dx.doi.org/10.2174/157017807781212175