Nicotinic and Glycinergic Medications for Disorders of Hedonic Regulation

Author(s): M.A. Dyer, R.S. Barr, A.E. Evins

Journal Name: Letters in Drug Design & Discovery

Volume 4 , Issue 5 , 2007

Become EABM
Become Reviewer


The majority of current smokers in the U.S. also have at least one comorbid psychiatric illness. Looking at commons mechanisms of nicotine dependence and psychiatric disorders of hedonic regulation reveals nicotinic acetylcholine receptors and the glycine site on NMDA receptors as potential targets for pharmacological treatment of these disorders.

Keywords: Nicotine dependence, Drug targets, Schizophrenia, Anhedonia, Nicotinic receptors, Glycine site/NMDA receptor

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2007
Page: [373 - 381]
Pages: 9
DOI: 10.2174/157018007780867852
Price: $65

Article Metrics

PDF: 1