Abstract
Pulmonary arterial hypertension is a feature of a spectrum of diseases that includes elevated pulmonary vascular resistance, induces right ventricular insufficiency and heart failure, and threatens the life. The aetiology and pathogenesis is diverse and associated with elevated morbidity and mortality. Treatment is frequently deficient and empirical. Fortunately, in recent years, randomized clinical trials have shown useful effects of various drugs on pulmonary arterial hypertension. This article reviews the pharmacological and not pharmacological therapeutic options to treat pulmonary arterial hypertension and attempts to provide a proposal of algorithm for its management based upon the evidence and available guidelines for clinical management.
Keywords: Pulmonary arterial hypertension, treatment
Current Respiratory Medicine Reviews
Title: Current Treatment of the Pulmonary Arterial Hypertension
Volume: 3 Issue: 2
Author(s): Juan C. Gallego-Page
Affiliation:
Keywords: Pulmonary arterial hypertension, treatment
Abstract: Pulmonary arterial hypertension is a feature of a spectrum of diseases that includes elevated pulmonary vascular resistance, induces right ventricular insufficiency and heart failure, and threatens the life. The aetiology and pathogenesis is diverse and associated with elevated morbidity and mortality. Treatment is frequently deficient and empirical. Fortunately, in recent years, randomized clinical trials have shown useful effects of various drugs on pulmonary arterial hypertension. This article reviews the pharmacological and not pharmacological therapeutic options to treat pulmonary arterial hypertension and attempts to provide a proposal of algorithm for its management based upon the evidence and available guidelines for clinical management.
Export Options
About this article
Cite this article as:
Gallego-Page C. Juan, Current Treatment of the Pulmonary Arterial Hypertension, Current Respiratory Medicine Reviews 2007; 3 (2) . https://dx.doi.org/10.2174/157339807780599117
DOI https://dx.doi.org/10.2174/157339807780599117 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Research Progress on Pathogenesis of Obesity-Induced Insulin Resistance and Its Therapeutic Targets: PPARα/γ
Current Signal Transduction Therapy Flavones as a Privileged Scaffold in Drug Discovery: Current Developments
Current Organic Synthesis Potential Roles of HDAC Inhibitors in Mitigating Ischemia-induced Brain Damage and Facilitating Endogenous Regeneration and Recovery
Current Pharmaceutical Design Novel Strategies for Preventing Diabetes and Obesity Complications with Natural Polyphenols
Current Medicinal Chemistry Cardiac Dys-Synchronization and Arrhythmia in Hyperhomocysteinemia
Current Neurovascular Research Efficacy of Topical Formulations in Healing of Caesarean Scars Using Non-Invasive Devices: A Controlled Trial
Applied Drug Research, Clinical Trials and Regulatory Affairs Biomarkers of Alcohol Consumption in Body Fluids - Possibilities and Limitations of Application in Toxicological Analysis
Current Medicinal Chemistry Management of Vasculopathy in Connective Tissue Disease
Current Rheumatology Reviews Placebos Used in Clinical Trials for Chinese Herbal Medicine
Recent Patents on Inflammation & Allergy Drug Discovery Developing Novel Therapeutic Approaches to Frailty
Current Pharmaceutical Design Pharmacophore, QSAR, and Binding Mode Studies of Substrates of Human Cytochrome P450 2D6 (CYP2D6) Using Molecular Docking and Virtual Mutations and an Application to Chinese Herbal Medicine Screening
Current Pharmaceutical Biotechnology Monocytes and Macrophages as Cellular Targets in Liver Fibrosis
Inflammation & Allergy - Drug Targets (Discontinued) Optimization of Important Early ADME(T) Parameters of NADPH Oxidase-4 Inhibitor Molecules
Medicinal Chemistry Recent Advances in Hematopoietic Stem Cell-Mediated Regeneration
Recent Patents on Regenerative Medicine Advances and Future Challenges in Adenoviral Vector Pharmacology and Targeting
Current Gene Therapy Advances in Stem Cells Transplantation for the Therapy of Parkinson’s Disease
Current Stem Cell Research & Therapy Cardioregulatory Functions of Neuropeptides and Peptide Hormones in Insects
Protein & Peptide Letters Prospects for Discovering the Secondary Metabolites of <i>Cordyceps</i> Sensu Lato by the Integrated Strategy
Medicinal Chemistry Targeting Antioxidants to Mitochondria: A Potential New Therapeutic Strategy for Cardiovascular Diseases
Current Pharmaceutical Design New Therapeutic Approaches to Arterial Calcification Via Inhibition of Transglutaminase andβ-Catenin Signalin
Current Pharmaceutical Design