Three-Component Synthesis of Dihydro-4-pyridones Catalyzed by Silica Sulfuric Acid

Author(s): Wei-Yi Chen, Xin-Sheng Li

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 2 , 2007

Become EABM
Become Reviewer


Three-component aza-Diels-Alder reactions of Danishefskys diene with aldehydes and amines took place smoothly to afford dihydro-4-pyridones with high yields in the presence of a catalytic amount of silica sulfuric acid (SSA). This new protocol consistently has the advantages of operational simplicity, economic consideration, and high yield.

Keywords: Aza-Diels-Alder reaction, aldehyde, amine, Danishefsky's diene, dihydro-4-pyridone, silica sulfuric acid

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2007
Page: [129 - 133]
Pages: 5
DOI: 10.2174/157017807780414082
Price: $65

Article Metrics

PDF: 1