Artemisinin, Promising Lead Natural Product for Various Drug Developments

Author(s): Seokjoon Lee

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 7 , Issue 4 , 2007

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Artemisinin and its synthetic derivatives are widely used for antimalarial agents in the world. Moreover, they are discovered to additionally use as anticancer, antiangiogenesis, antiviral, immunosuppressive, and antifungal agents. Recent research results supported that it is a very promising field in drug discovery. In this review, it will discuss the structural and biological features of artemisinin and its derivatives that have published since 2003 except antimalarial, and show that they are useful lead compounds for novel drug discovery.

Keywords: Artemisinin, artemisinin derivatives, natural product, endoperoxide, lead compound, drug discovery

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Article Details

Year: 2007
Page: [411 - 422]
Pages: 12
DOI: 10.2174/138955707780363837
Price: $65

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PDF: 11