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Letters in Drug Design & Discovery

Editor-in-Chief

ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Synthesis and Antimicrobial Activity of Pyridine Derivatives Substituted at C-2 and C-6 Positions

Author(s): Mauro Vieira De Almeida, Marcus Vinicius de Nora Souza, Nadia Rezende Barbosa, Frederico Pittella Silva, Giovanni Wilson Amarante and Sílvia Helena Cardoso

Volume 4, Issue 2, 2007

Page: [149 - 153] Pages: 5

DOI: 10.2174/157018007779422514

Price: $65

Abstract

A series of C-2 and C-6 substituted pyridines was synthesized and evaluated in vitro against Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus mutans and Candida albicans. Most of compounds exhibited a wide range of modest in vitro activity against the tested microorganisms.

Keywords: Substituted pyridines, Amide, Antimicrobial activity, Synthesis


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