Currently Available Drugs for the Treatment of Obesity: Sibutramine and Orlistat

Author(s): J.-P. Chaput, S. St-Pierre, A. Tremblay

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 7 , Issue 1 , 2007

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The currently available drugs for long-term treatment of obesity are sibutramine and orlistat. They have been shown to be able to induce significant weight loss, with important co-morbidity reduction, allowing the maintenance of reduced body weight for at least 1-2 years. Cardiostimulating and gastrointestinal adverse effects are however not negligible.

Keywords: Pharmacotherapy, sibutramine, orlistat, body weight, fat, energy balance, physical activity, diet

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Article Details

Year: 2007
Page: [3 - 10]
Pages: 8
DOI: 10.2174/138955707779317849

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