Abstract
The currently available drugs for long-term treatment of obesity are sibutramine and orlistat. They have been shown to be able to induce significant weight loss, with important co-morbidity reduction, allowing the maintenance of reduced body weight for at least 1-2 years. Cardiostimulating and gastrointestinal adverse effects are however not negligible.
Keywords: Pharmacotherapy, sibutramine, orlistat, body weight, fat, energy balance, physical activity, diet
Mini-Reviews in Medicinal Chemistry
Title: Currently Available Drugs for the Treatment of Obesity: Sibutramine and Orlistat
Volume: 7 Issue: 1
Author(s): J.-P. Chaput, S. St-Pierre and A. Tremblay
Affiliation:
Keywords: Pharmacotherapy, sibutramine, orlistat, body weight, fat, energy balance, physical activity, diet
Abstract: The currently available drugs for long-term treatment of obesity are sibutramine and orlistat. They have been shown to be able to induce significant weight loss, with important co-morbidity reduction, allowing the maintenance of reduced body weight for at least 1-2 years. Cardiostimulating and gastrointestinal adverse effects are however not negligible.
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Cite this article as:
Chaput J.-P., St-Pierre S. and Tremblay A., Currently Available Drugs for the Treatment of Obesity: Sibutramine and Orlistat, Mini-Reviews in Medicinal Chemistry 2007; 7 (1) . https://dx.doi.org/10.2174/138955707779317849
DOI https://dx.doi.org/10.2174/138955707779317849 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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