Production of Tablet-Like Solid Bodies Without Pressure by Sol-Gel Processes

Nadine      Pachulski; Joachim      Ulrich

Abstract

A sol-gel and a freeze-casting process are used to produce tablet-like bodies without the standard compression. The advantage is that temperature sensible materials can be produced in tablet-like forms, thus other cost intensive production processes like capsulation or freeze drying are avoided. Different ways are introduced to characterize the suspension and the tablet. Herewith the influences of parameters like composition of the materials or freezing conditions on the final products should be clarified.

Keywords: Sol-gel, Freeze casting, Tablet, Pressure free tabletting, Tablet-like body, Cold compression

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Letters in Drug Design & Discovery

Title: Production of Tablet-Like Solid Bodies Without Pressure by Sol-Gel Processes

Volume: 4 Issue: 1

Author(s): Nadine Pachulski and Joachim Ulrich

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Keywords: Sol-gel, Freeze casting, Tablet, Pressure free tabletting, Tablet-like body, Cold compression

Abstract: A sol-gel and a freeze-casting process are used to produce tablet-like bodies without the standard compression. The advantage is that temperature sensible materials can be produced in tablet-like forms, thus other cost intensive production processes like capsulation or freeze drying are avoided. Different ways are introduced to characterize the suspension and the tablet. Herewith the influences of parameters like composition of the materials or freezing conditions on the final products should be clarified.

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Pachulski Nadine and Ulrich Joachim, Production of Tablet-Like Solid Bodies Without Pressure by Sol-Gel Processes, Letters in Drug Design & Discovery 2007; 4 (1) . https://dx.doi.org/10.2174/157018007778992919