Title: A Commentary on Neuronal Degeneration and Cell Death in Guam ALS and PD: An Evolutionary Process of Understanding
VOLUME: 3 ISSUE: 4
Author(s):Ralph M. Garruto
Affiliation:Binghamton University,SUNY, Departments of Anthropology and Biological Sciences, PO Box 6000, Science 1, Room 113, Binghamton, New York 13902-6000, USA.
Keywords:Gene-environment interaction, mitochondrial dysfunction, genetic susceptibility
Abstract: The Twentieth Century witnessed tremendous advances in our understanding of neurodegenerative diseases. Not least among them were the contributions from hyperendemic foci of neurodegenerative disorders in isolated human groups worldwide, with the knowledge gained applicable to our understanding of related neurodegenerative diseases globally.