Title: Practical Method for Parallel Synthesis of Diversely Substituted 1- henylpiperazines
VOLUME: 8 ISSUE: 9
Author(s):Igor Konstantinov, Konstantin Bukhryakov, Yuri Gezentsvey and Mikhail Krasavin
Affiliation:Science and Education Center “Innovative Research”, Yaroslavl State Pedagogical University, 150000, Russia.
Keywords:Bis-alkylation, N-arylpiperazines, nitrogen mustard, parallel synthesis, solvent-free synthesis, SAR-informative, 1-phenylpiperazines, morpholine, iminodiethanol, ethanamine
Abstract: A simple and practical method to prepare ‘libraries’ of substituted 1-phenylpiperazine building blocks in parallel format has been developed.