Practical Method for Parallel Synthesis of Diversely Substituted 1- henylpiperazines

Author(s): Igor Konstantinov, Konstantin Bukhryakov, Yuri Gezentsvey, Mikhail Krasavin

Journal Name: Letters in Organic Chemistry

Volume 8 , Issue 9 , 2011

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Abstract:

A simple and practical method to prepare ‘libraries’ of substituted 1-phenylpiperazine building blocks in parallel format has been developed.

Keywords: Bis-alkylation, N-arylpiperazines, nitrogen mustard, parallel synthesis, solvent-free synthesis, SAR-informative, 1-phenylpiperazines, morpholine, iminodiethanol, ethanamine

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Article Details

VOLUME: 8
ISSUE: 9
Year: 2011
Page: [628 - 630]
Pages: 3
DOI: 10.2174/157017811799304386
Price: $65

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