A Facile Route for the Regioselective Deacetylation of Peracetylated Carbohydrates at Anomeric Position

Author(s): Srinivas Chittaboina, Blake Hodges, Qian Wang

Journal Name: Letters in Organic Chemistry

Volume 3 , Issue 1 , 2006

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The regioselective 1-O-deacetylation of peracetylated carbohydrates with ammonium acetate in DMF (or a mixed solution of tetrahydrofuran and methanol) is described. It offers a facile and efficient way to prepare O-acetylpyranosides presenting one free hydroxyl group at the anomeric position.

Keywords: Carbohydrates, regioselectivity, glycosides, acylation, glycosylations

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Article Details

Year: 2006
Page: [35 - 38]
Pages: 4
DOI: 10.2174/157017806774964521

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