Generic placeholder image

Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

The Enantiomeric Differentiation Ability of Chiral Crown Ethers Based on Carbohydrates

Author(s): Peter Bako, Gyorgy Keglevich, Zsolt Rapi and Laszlo Toke

Volume 16, Issue 3, 2012

Page: [297 - 304] Pages: 8

DOI: 10.2174/138527212799499877

Abstract

The enantiomeric differentiation ability of chiral sugar-based crown ethers can be utilized for the determination of the enantiomeric composition of chiral amino compounds and for the separation of racemic amino compounds. Chiral crown ethers incorporating various carbohydrate units in the macrocyclic structure showing enantiomeric recognition towards chiral primary amines, amino acids and amino acid esters are reviewed here. The chiral recognition of organic ammonium salts by crown ethers may be tested with various methods. In this review, practical applications are also summarized, where the enantiomers of racemic amino compounds and their derivatives are separated by carbohydrate-based crown ethers immobilized on a stationary phase.

Keywords: Chiral crown ethers, carbohydrate-based crown ethers, enantiomeric recognition, enantiomer separation

Next »

© 2024 Bentham Science Publishers | Privacy Policy