Chromenopyridines: Promising Scaffolds for Medicinal and Biological Chemistry

Author(s): L. J. Nunez-Vergara, J. A. Squella, P. A. Navarrete-Encina, E. Vicente-Garcia, S. Preciado, R. Lavilla

Journal Name: Current Medicinal Chemistry

Volume 18 , Issue 31 , 2011

Become EABM
Become Reviewer

Abstract:

Chromenopyridines constitute a structurally diverse class of compounds with a wide range of bioactivities and increasing presence in drugs. Here we analyze the scope of the synthetic methodology to access this nucleus with emphasis on multicomponent reactions and robust methodologies. Reactivity issues, medicinal applications and other properties are also reviewed.

Keywords: Azines, benzopyran, chromene, coumarin, drug-like scaffolds, heterocycles, multicomponent reactions, privileged structures, pyridine, synthetic methods

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 18
ISSUE: 31
Year: 2011
Page: [4761 - 4785]
Pages: 25
DOI: 10.2174/092986711797535272
Price: $65

Article Metrics

PDF: 3