The Application of Trialkoxysilane as Transmetallation Reagent in Organic Synthesis

Author(s): Fang Luo, Changduo Pan, Jiang Cheng

Journal Name: Current Organic Chemistry

Volume 15 , Issue 16 , 2011


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Abstract:

Organosilicon compounds are important transmetallation reagents in organic synthesis. Aryltrialkoxysilane have recently emerged as an attractive alternative to traditional organometallic donors, due to their ease of handling, stability toward air/moisture, and/or low toxicity compared to some of the other organometallic reagents (Zn, Mg, Sn, etc.). In this review, the application of aryl trialkoxysilane and alkenyltrialkoxysilane as transmetallation reagent for C-C, C-N, C-S and C-O bonds formation will be disclosed.

Keywords: Organosilicon, transmetallation reagent, organic synthesis, organostannanes, Hiyama Reaction, arylsiloxane, -substituted ketones, aldehydes, esters, nitriles, nitroalkanes, enamide derivatives, trialkoxysilane, trialkoxysilanes

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Article Details

VOLUME: 15
ISSUE: 16
Year: 2011
Published on: 01 March, 2012
Page: [2816 - 2829]
Pages: 14
DOI: 10.2174/138527211796378514
Price: $65

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