Acute Management in Very Old Patients: Is Thrombolysis Safe?

Author(s): Fabiana Ortega, Maria C. Zurru

Journal Name: Cardiovascular & Hematological Disorders-Drug Targets
Formerly Current Drug Targets - Cardiovascular & Hematological Disorders

Volume 11 , Issue 1 , 2011

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In our analysis, patients who were treated with intravenous rt-PA had a better outcome than untreated patients, and this effect was not dependent on age. The weight of evidence to date indicates a potential for benefit in older people, and there is no a priori reason to suspect a diminished effect when compared with younger people. The risk of bleeding is similar in both groups. We believe that clinical treatment guidelines should be revised in order to remove the age restriction in the use of intravenous rt-PA acute ischemic stroke.

Keywords: NINDS rt-PA, INTRACRANIAL BLEEDING, octogenarians, rt-PA, elderly, thrombolysis, Acute ischemic stroke

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Article Details

Year: 2011
Page: [6 - 8]
Pages: 3
DOI: 10.2174/187152911795945204

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PDF: 13