Virtual Screening Against Obesity

Author(s): P. Markt, S. Herdlinger, D. Schuster

Journal Name: Current Medicinal Chemistry

Volume 18 , Issue 14 , 2011

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Abstract:

The development of novel drugs against obesity is one of the top priorities of worldwide drug research. In recent years, it has been facilitated by the application of virtual screening methods. In this review, we give a short introduction into obesity-related protein targets and computer-aided drug design techniques. Furthermore, we highlight the most successful virtual screening studies, outline their results, and provide suggestions for future anti-obesity drug development.

Keywords: Anti-obesity drug, computer-aided drug design, ligand-based, molecular mechanisms, obesity, obesity targets, structure-based, virtual screening, screening studies

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Article Details

VOLUME: 18
ISSUE: 14
Year: 2011
Page: [2158 - 2173]
Pages: 16
DOI: 10.2174/092986711795656162
Price: $65

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