Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy

Author(s): P. F. Jiao, H. Y. Zhou, L. X. Chen, B. Yan

Journal Name: Current Medicinal Chemistry

Volume 18 , Issue 14 , 2011

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Abstract:

Nanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.

Keywords: Gold nanoparticles, targeting moieties, therapeutic payloads, conjugation methods, cancer imaging, cancer therapy, Nanotechnology, multifunctionalized, cancer-targeting

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Article Details

VOLUME: 18
ISSUE: 14
Year: 2011
Page: [2086 - 2102]
Pages: 17
DOI: 10.2174/092986711795656199
Price: $65

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