Abstract
The interest in analytical ultracentrifugation (AUC) to analyze protein structural parameters and interactions has increased in the past decades as a result of several developments on new generation instrumentation and data analysis tools. In this article, we review AUC principles and applications to study proteins, emphasizing molecular targets of Mycobacterium tuberculosis.
Keywords: Analytical ultracentrifugation, protein folding, Mycobacterium tuberculosis, protein structure-function, anti-tuberculosis agents, high centrifugal force, hydrodynamic parameters, sedimentation, colloids, macromolecules
Current Medicinal Chemistry
Title: Analysis of Molecular Targets of Mycobacterium tuberculosis by Analytical Ultracentrifugation
Volume: 18 Issue: 9
Author(s): J. C. Borges and C. H.I. Ramos
Affiliation:
Keywords: Analytical ultracentrifugation, protein folding, Mycobacterium tuberculosis, protein structure-function, anti-tuberculosis agents, high centrifugal force, hydrodynamic parameters, sedimentation, colloids, macromolecules
Abstract: The interest in analytical ultracentrifugation (AUC) to analyze protein structural parameters and interactions has increased in the past decades as a result of several developments on new generation instrumentation and data analysis tools. In this article, we review AUC principles and applications to study proteins, emphasizing molecular targets of Mycobacterium tuberculosis.
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Cite this article as:
C. Borges J. and H.I. Ramos C., Analysis of Molecular Targets of Mycobacterium tuberculosis by Analytical Ultracentrifugation, Current Medicinal Chemistry 2011; 18 (9) . https://dx.doi.org/10.2174/092986711795029537
DOI https://dx.doi.org/10.2174/092986711795029537 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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