Atom Probe Tomography – A High Throughput Screening Tool for Atomic Scale Chemistry

Author(s): Krishna Rajan

Journal Name: Combinatorial Chemistry & High Throughput Screening
Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 14 , Issue 3 , 2011

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The objective of this paper is to examine the challenges and opportunities in high throughput screening of atomic scale chemistry via a technique known as atom probe tomography. While there are numerous methods that exist in the field of throughput screening, even at the nanoscale, most of the effort is on screening properties, rather than chemistry and/or structure. In this overview, we discuss the role atom probe tomography can have as a high throughput screening tool of atomic scale chemistry. Particular emphasis on the study of organic/biological materials is given along with the needs and challenges to make atom probe tomography more widespread in the field of combinatorial chemistry.

Keywords: Atom probe tomography, atomic scale chemistry, data, informatics, organic films, High Throughput Screening, ion microscopy, microanalysis technique, atomic resolution, field-ion microscope, microelectromechanical systems

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Article Details

Year: 2011
Page: [198 - 205]
Pages: 8
DOI: 10.2174/138620711794728707
Price: $65

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