Abstract
Over the past two decades, glycosylated nanoparticles (i.e., glyconanoparticles having sugar residues on the surface) received much attention for biomedical applications such as bioassays and targeted drug delivery. This minireview focuses on three aspects: (1) glycosylated gold nanoparticles, (2) glycosylated quantum dots, and (3) glyconanoparticles self-assembled from amphiphilic glycopolymers. The synthetic methods and the multivalent interactions between glyconanoparticles and lectins is shortly illustrated.
Keywords: Glyconanoparticles, glycopolymers, biomolecular recognition, bioassays, targeted drug delivery, multivalent interactions, biological receptors, cell adhesion, carbohydrate-protein interactions, magnetic resonance imaging, colloidal stability, water-solubility, biodegradable, glycopolymer
Combinatorial Chemistry & High Throughput Screening
Title: Glyconanoparticles for Biomedical Applications
Volume: 14 Issue: 3
Author(s): Chang-Ming Dong
Affiliation:
Keywords: Glyconanoparticles, glycopolymers, biomolecular recognition, bioassays, targeted drug delivery, multivalent interactions, biological receptors, cell adhesion, carbohydrate-protein interactions, magnetic resonance imaging, colloidal stability, water-solubility, biodegradable, glycopolymer
Abstract: Over the past two decades, glycosylated nanoparticles (i.e., glyconanoparticles having sugar residues on the surface) received much attention for biomedical applications such as bioassays and targeted drug delivery. This minireview focuses on three aspects: (1) glycosylated gold nanoparticles, (2) glycosylated quantum dots, and (3) glyconanoparticles self-assembled from amphiphilic glycopolymers. The synthetic methods and the multivalent interactions between glyconanoparticles and lectins is shortly illustrated.
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Cite this article as:
Dong Chang-Ming, Glyconanoparticles for Biomedical Applications, Combinatorial Chemistry & High Throughput Screening 2011; 14 (3) . https://dx.doi.org/10.2174/138620711794728716
DOI https://dx.doi.org/10.2174/138620711794728716 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
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