Abstract
Electrochemical redox compounds, which can interact or bind with different affinities to single and double stranded DNA and thus are referred to as electrochemical hybridization indicators, represent a powerful and, along with this, simple tool for electrochemical genetic analysis. In this paper, general tendencies and recent advances in this field, including the modes of DNA-redox indicators interactions, approaches for their electrochemical analysis, and applications in electrochemical DNA assays are overviewed. This is a critical mini-review with 122 references.
Keywords: Electrochemical biosensors, DNA hybridization, Genosensors, Electrochemical redox indicators, Intercalator, Methylene blue, electrochemical genetic analysis, piezoelectric, SPR devices, redox active compounds, alkanethiol linker, ethidium bromide, acridine derivatives, thracyclines, phenothiazines, metalointercalator, GROOVE-BINDING REDOX INDICATORS, Hoecht 33258, Metalointercalators, Helicobacter pylori, Anthraquinone, Organic Intercalators, daunomycin, benzyl viologen, viologen dimer, mercaptohexyl, phenothiazine dye
Current Analytical Chemistry
Title: Electrochemical Indicators for DNA Electroanalysis
Volume: 7 Issue: 1
Author(s): Elena E. Ferapontova
Affiliation:
Keywords: Electrochemical biosensors, DNA hybridization, Genosensors, Electrochemical redox indicators, Intercalator, Methylene blue, electrochemical genetic analysis, piezoelectric, SPR devices, redox active compounds, alkanethiol linker, ethidium bromide, acridine derivatives, thracyclines, phenothiazines, metalointercalator, GROOVE-BINDING REDOX INDICATORS, Hoecht 33258, Metalointercalators, Helicobacter pylori, Anthraquinone, Organic Intercalators, daunomycin, benzyl viologen, viologen dimer, mercaptohexyl, phenothiazine dye
Abstract: Electrochemical redox compounds, which can interact or bind with different affinities to single and double stranded DNA and thus are referred to as electrochemical hybridization indicators, represent a powerful and, along with this, simple tool for electrochemical genetic analysis. In this paper, general tendencies and recent advances in this field, including the modes of DNA-redox indicators interactions, approaches for their electrochemical analysis, and applications in electrochemical DNA assays are overviewed. This is a critical mini-review with 122 references.
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Cite this article as:
E. Ferapontova Elena, Electrochemical Indicators for DNA Electroanalysis, Current Analytical Chemistry 2011; 7 (1) . https://dx.doi.org/10.2174/157341111793797617
DOI https://dx.doi.org/10.2174/157341111793797617 |
Print ISSN 1573-4110 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6727 |
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