Synthesis of Functionalized Chromenes from Meldrum’s Acid, 4- Hydroxycoumarin, and Ketones or Aldehydes

Title:Synthesis of Functionalized Chromenes from Meldrum’s Acid, 4- Hydroxycoumarin, and Ketones or Aldehydes

VOLUME: 13 ISSUE: 9

Author(s):Maryam Sabbaghan, Issa Yavari and Zinatossadat Hossaini

Affiliation:Faculty of Sciences, Chemistry Department, Shahid Rajaee Teacher Training University, P.O. Box 16785-163, Tehran, Iran.

Keywords:Chromene, proline, aqueous media, meldrum’s acid, 4-hydroxycoumarin

Abstract:An efficient synthesis of 4-alkyl-4-methyl-3,4-dihydro-2H,5H-pyrano[3,2-c]chromene-2,5-dione or 4-aryl-3,4- dihydro-2H,5H-pyrano[3,2-c]chromene-2,5-diones via reaction 4-hydroxycoumarin with Meldrum’s acid and ketones or aldehydes is described.

Cite this article as:

Maryam Sabbaghan, Issa Yavari and Zinatossadat Hossaini, “Synthesis of Functionalized Chromenes from Meldrum’s Acid, 4- Hydroxycoumarin, and Ketones or Aldehydes”, Combinatorial Chemistry & High Throughput Screening (2010) 13: 813. https://doi.org/10.2174/138620710792927358

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